Bricanyl - Terbutaline

AstraZeneca

Description

Short-acting selective beta2 agonist.

For asthma
By mouth
Adult: 2.5 mg 3 times a day for 1–2 weeks, then increased to up to 5 mg 3 times a day, use by inhalation preferred over by mouth.
By subcutaneous injection, or slow intravenous injection
Adult:250–500 micrograms up to 4 times a day, reserve intravenous beta₂ agonists for those in whom inhaled therapy cannot be used reliably or there is no current effect.
By continuous intravenous infusion
Adult: 90–300 micrograms/hour for 8-10 hours, to be administered as a solution containing 3–5 micrograms/mL, high doses require close monitoring, reserve intravenous beta₂ agonists for those in whom inhaled therapy cannot be used reliably or there is no current effect.
By inhalation of powder
Adult: 500 micrograms up to 4 times a day, for persistent symptoms.
By inhalation of nebulised solution
Adult: 5–10 mg 2–4 times a day, additional doses may be necessary in severe acute asthma.

For acute asthma
By subcutaneous injection, or by slow intravenous injection
• Child 2–14 years: 10 mcg/kg up to four times/day (maximum per dose 300 mcg)
• Child 15–17 years: 250–500 mcg up to four times/day
By continuous intravenous infusion
• Child: loading dose of 2–4 mcg/kg, then 1–10 mcg/kg/hour

For moderate, severe, or life-threatening acute asthma (given via oxygen-driven nebuliser if available)
• Child 1 month–4 years: 5 mg, repeated every 20–30 minutes or when required.
• Child 5–11 years: 5–10 mg, repeated every 20–30 minutes or when required.
• Over 12 years: 10 mg, repeated every 20–30 minutes or when required.

Exacerbation of reversible airway obstruction (including nocturnal asthma), prevention of exercise-induced bronchospasm
By inhalation of powder
• Child 5–17 years: 500 mcg up to four times/day
By mouth
• Child 1 month–6 years: 75 mcg/kg three times/day (maximum per dose 2.5 mg)
• Child 7–14 years: 2.5 mg 2–3 times daily
• Child 15–17 years: 2.5 mg three times/day, then increased if necessary to 5 mg three times/day.