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Respiratory Handbook

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Ipratropium bromide - Medihealth (Northern) Ltd

Medihealth (Northern) Ltd

Description

Antimuscarinic bronchodilator.

Reversible airway obstruction by inhalation of aerosol
• Child 1 month–5 years: 20 mcg, 3 times daily.
• Child 6–11 years: 20–40 mcg, 3 times daily.
• Over 12 years: 20–40 mcg, 3–4 times daily.

For reversible airways obstruction in COPD by inhalation of nebulised solution
• Adult: 250–500 mcg, 3–4 times daily.

For reversible airways obstruction in COPD by inhalation of aerosol
• Adult: 20–40 mcg, 3–4 times daily.

Severe or life-threatening acute asthma by inhalation of nebulised solution
• Child 1 month–11 years: 250 mcg, every 20–30 minutes, for the first two hours, then repeat every 4–6 hours, as required.
• Over 12 years: 500 mcg, every 4–6 hours, as required.

Acute bronchospasm by inhalation of nebulised solution
• Child 1 month–5 years: 125–250 mcg, maximum 1 mg daily.
• Child 6–11 years: 250 mcg, maximum 1 mg daily.
• Over 12 years: 500 mcg, repeated as necessary, usual maximum 2 mg daily. Doses higher than the recommended maximum can be given under medical supervision.

Rhinorrhoea associated with allergic and non-allergic rhinitis by intranasal administration
• Over 12 years: 2 sprays, 2–3 times/day into each nostril.

Indications

For the management of reversible airway obstructions, particularly in COPD, and rhinitis.

Ipratropium can provide short-term relief in chronic asthma, but short-acting beta2 agonists are preferred as they act more quickly.

The aerosol inhalation of ipratropium can be used for short-term relief in mild COPD in patients who are not using a long-acting antimuscarinic drug. Its maximal effect occurs 30–60 minutes after use. Its duration of action is three to six hours and bronchodilation can usually be maintained with treatment three times a day.

Preparations Available

Spray

Sizes Available

250 mcg/1 ml, 20 doses 
500 mcg/2 ml, 20 doses 

More on: Bronchodilators , Antimuscarinic bronchodilators