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Respiratory Handbook

The professional's guide to product selection

SIGMA Pharmaceuticals

SIGMA Pharmaceuticals

SIGMA Pharmaceuticals
Unit 1-7 Imperial Way
Watford

Hertfordshire
WD24 4YR
+44 (0)1923 444999

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SIGMA Pharmaceuticals Products

Budesonide - Sigma Pharmaceuticals Plc

Prophylaxis and treatment of allergic rhinitis and nasal polyps by intranasal administration
• Over 6 years: 256 mcg once daily, to be administered as 2 sprays into each nostril in the morning, reduce dose when control achieved. Alternatively, 128 mcg…

Carbocisteine - Sigma Pharmaceuticals Plc

Mucolytic to facilitate expectoration.

• Child 2–4 years: 62.5–125 mg, 4 times daily
• Child 5–11 years: 250 mg, 3 times daily
• Over 12 years: initially 2.25 g daily in divided doses, then 1.5 g daily in divided doses as condition improves.

Chlorphenamine maleate - Sigma Pharmaceuticals Plc

Sedating antihistamine.

By mouth for symptomatic relief of allergy such as hay fever, urticaria, food allergy, drug reactions, relief of itch associated with chickenpox.


• Child 1–23 months: 1 mg, twice daily.
• Child 2–5 years: 1 mg, every 4–6 hours,…

Dexamethasone - Sigma Pharmaceuticals Plc

Suppression of inflammatory and allergic disorders by mouth
• Child: 10–100 mcg/kg daily in 1 or 2 divided doses. Up to 300 mcg/kg can be given in emergency situations. 
• Adult: 0.5–10 mg daily.

Mild croup by mouth
• Child: 150 mcg/kg for 1 dose.

Severe …

Ephedrine hydrochloride - Sigma Pharmaceuticals Plc

A non-specific adrenoceptor agonist.

For reversible airway obstruction by mouth
Adult: 15–60 mg 3 times a day.

Nasal congestion, sinusitis affecting the maxillary antrum by intranasal administration
Child 12-17 years: Apply 1–2 drops up to 4 times a da…

Hydrocortisone - Sigma Pharmaceuticals Plc

For the treatment of anaphylaxis and asthma.

By intravenous injection for acute hypersensitivity reactions
• Adult: 100–300 mg, to be administered as sodium succinate.

By intramuscular injection, or by intravenous injection for acute hypersensitivity r…

Ipratropium bromide - Sigma Pharmaceuticals Plc

Antimuscarinic bronchodilator.

Reversible airway obstruction by inhalation of aerosol
• Child 1 month–5 years: 20 mcg, 3 times daily.
• Child 6–11 years: 20–40 mcg, 3 times daily.
• Over 12 years: 20–40 mcg, 3–4 times daily.

For reversible airways obstr…

Mometasone furoate - Sigma Pharmaceuticals Plc

Prophylaxis and treatment of allergic rhinitis by intranasal administration
• Child 3–11 years: 50 mcg daily, dose into each nostril.
• Over 12 years: 100 mcg daily, increased if necessary up to 200 mcg daily, dose into each nostril. Reduce to 50 mcg d…

Montelukast - Sigma Pharmaceuticals

A leukotriene receptor antagonist that inhibits bronchoconstriction by blocking the inflammatory response in the airways.

Prophylaxis of asthma
• Child 6 months–5 years: 4 mg once daily in the evening.
• 6–14 years: 5 mg once daily in the evening.
• Adu…

Prednisolone - Sigma Pharmaceuticals Plc

By mouth for acute exacerbation of chronic obstructive pulmonary disease
• Adult: 30 mg daily for 7–14 days.

By mouth for severe croup or mild croup that might cause complications (before transfer to hospital)
• Child: 1–2 mg/kg.

By mouth for mild to mod…