Vertex
Vertex
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Vertex Products
Kaftrio - Tezacaftor with Ivacaftor and Elexacaftor
Mucolytic to facilitate expectoration by reducing sputum viscosity in the case of cystic fibrosis.
Kaftrio 37.5 mg/25 mg/500 mg
Child 6–11 years (body-weight up to 30 kg): 2 tablets, to be taken in the morning and, Ivacaftor 75 mg to be taken in the e…
Kalydeco - Ivacaftor
A cystic fibrosis transmembrane conductance regulator (CFTR) protein potentiator that increases chloride transport in the abnormal CFTR protein.
By mouth using granules
Child 4–5 months (body-weight 5 kg and above): 25 mg every 12 hours.
Child 6 months…
Orkambi - Lumacaftor with Ivacaftor
Lumacaftor increases the number of proteins that each the cell surface. Ivacaftor is a cystic fibrosis transmembrane conductance regulator (CFTR) protein potentiator that increases chloride transport in the abnormal CFTR protein.
By mouth using granu…
Symkevi - Tezacaftor with Ivacaftor
Mucolytic to facilitate expectoration by reducing sputum viscosity in the case of cystic fibrosis.
By mouth
Child 6–11 years (body-weight up to 30 kg): 50/75 mg, to be taken in the morning and, Ivacaftor 75 mg to be taken in the evening (about 12 hour…