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Respiratory Handbook

The professional's guide to product selection

Compound preparations

AirFluSal - Salmeterol and fluticasone propionate

Long-acting selective beta2 agonist with corticosteroid.

AirFluSal 125
• Adult for prophylaxis of moderate to severe asthma: two inhalations twice daily.

AirFluSal 250
• Over 18 years for prophylaxis of moderate to severe asthma: two inhalations twice daily.

AirFluSal Forspiro
• Adult for severe asthma and COPD: one inhalation twice a day.

Aloflute and Sirdupla - Salmeterol and fluticasone propionate

Long-acting selective beta2 agonist with corticosteroid.

Prophylaxis of moderate-to-severe asthma for Aloflute® 25/125 by inhalation of aerosol
Adult: 2 inhalations twice daily.

Prophylaxis of moderate-to-severe asthma for Aloflute® 25/250 by inhalation of aerosol
Adult: 2 inhalations twice daily.

Anoro Ellipta - Umeclidinium with vilanterol

Antimuscarinic bronchodilator with long-acting selective beta2 agonist.

• Adult over 18 years for maintenance treatment of COPD: by inhalation of powder, 1 inhalation, once daily.

Avenor - Salmeterol and fluticasone

For prophylaxis of asthma with Avenor® 25/125 by inhalation of aerosol
Child 12–17 years: 2 inhalations twice daily.
Adult: 2 inhalations twice daily.

For prophylaxis of asthma with Avenor® 25/250 by inhalation of aerosol
Child 12–17 years: 2 inhalations twice daily.
Adult: 2 inhalations twice daily.

For prophylaxis of asthma with Avenor® 25/50 by inhalation of aerosol
Child 4–17 years: 2 inhalations twice daily, reduced to 2 inhalations once daily, use reduced dose only if control maintained.
Adult: 2 inhalations twice daily, reduced to 2 inhalations once daily, use reduced dose only if control maintained.

Combiprasal - Ipratropium bromide with salbutamol

Antimuscarinic bronchodilator with short-acting selective beta2 agonist.

• Adult and child over 12 years for bronchospasm in chronic obstructive pulmonary disease: by inhalation of nebulised solution, 0.5/2.5 mg, 3–4 times daily.

Combisal - Salmeterol and fluticasone propionate

Long-acting selective beta2 agonist with corticosteroid.

Combisal 25/125
• Over 12 years for prophylaxis of asthma: two inhalations twice daily.
Combisal 25/50
• Over 4 years for prophylaxis of asthma: two inhalations twice daily, but can be reduced to two inhalations once daily.
Combisal 25/250
• Over 12 years for prophylaxis of asthma: two inhalations twice daily.

DuoResp Spiromax - Budesonide with formoterol

Long-acting selective beta2 agonist with corticosteroid.

DuoResp Spiromax 160 mcg/4.5 mcg
• Adult for asthma maintenance: one to two inhalations twice daily, and up to four inhalations twice daily.
• Adult for asthma maintenance and reliever therapy: two inhalations twice daily across one or two doses, and increased to two inhalations twice daily if needed. One inhalation taken as required to relieve symptoms and increased up to six if needed but with a maximum of eight inhalations per day. Up to 12 inhalations can be taken per day for a limited time under medical supervision.
• Adult for COPD: two inhalations twice daily.

DuoResp Spiromax 320 mcg/9 mcg
• Adult for asthma maintenance: one inhalation twice daily, but increased to two inhalations twice daily if required.
• Adult for COPD: one inhalation twice daily.

Fixkoh Airmaster - Salmeterol and fluticasone propionate

Long-acting selective beta2 agonist with corticosteroid.


Fixkoh Airmaster 50/100
• 12 years and over for prophylaxis of asthma: one inhalation twice daily but can be reduced to once daily.
Fixkoh Airmaster 50/250
• 12 years and over for prophylaxis of asthma: one inhalation twice daily.
Fixkoh Airmaster 50/500
• 12 years and over for prophylaxis of asthma: one inhalation twice daily.
• Adult for COPD: 1 inhalation twice daily.

Flutiform - Fluticasone propionate and formoterol fumarate

Long-acting selective beta2 agonist with corticosteroid.

Flutiform 50
• Over 5 years for prophylaxis of asthma: two puffs twice daily.

Flutiform 125
• Over 12 years by aerosol inhalation for prophylaxis of asthma: two puffs twice daily.

Flutiform 250
• Adult for prophylaxis of asthma: two puffs twice daily.

Flutiform K-haler 50
• Over 12 years by aerosol inhalation for prophylaxis of asthma: two puffs twice daily.

Flutiform K-haler 125
• Over 12 years by aerosol inhalation for prophylaxis of asthma: two puffs twice daily.

Fobumix Easyhaler - Budesonide with formoterol

Long-acting selective beta2 agonist with corticosteroid.

Fobumix 80/4.5 Easyhaler
• Adult for asthma maintenance: one to two inhalations twice daily, but increased to four inhalations twice daily if required.
• Adult for asthma maintenance and relief therapy: two inhalations daily across one or two doses. One inhalation can be used for relief of symptoms up to six doses with a maximum of eight per day. Twelve doses can be administered per day for a short time under medical supervision.

Fobumix 160/4.5 Easyhaler
• Adult for asthma maintenance: one to two inhalations twice daily, but increased to four inhalations twice daily if required.
• Adult for asthma maintenance and relief therapy: two inhalations daily across one or two doses, increased to two inhalations twice daily if needed. One inhalation can be used for relief of symptoms up to six doses with a maximum of eight per day. Twelve doses can be administered per day for a short time under medical supervision.
• Adult for COPD: two inhalations twice daily.

Fobumix 320/9 Easyhaler
• Adult for asthma maintenance: one inhalation twice daily, but increased to two inhalations twice daily if required.
• Adult for COPD: one inhalation twice daily.

Fostair - Beclometasone with formoterol

Long-acting selective beta2 agonist with corticosteroid.

Fostair NEXThaler 200/6
• Adult for asthma maintenance therapy: two inhalations twice daily, with a maximum of four inhalations per day.

Fostair NEXThaler 100/6
• Adult for asthma maintenance therapy: one to two inhalations twice daily, with a maximum of four inhalations per day.
• Adult for asthma maintenance and reliever therapy: one inhalations twice daily, with a maximum of eight inhalations per day.
• Adult for COPD with FEV1 <50% predicted: two inhalations twice daily.

Fostair 100/6
• Adult for asthma maintenance therapy: one to two inhalations twice daily, with a maximum of four inhalations per day.
• Adult for asthma maintenance and reliever therapy: one inhalations twice daily, with a maximum of eight inhalations per day.
• Adult for COPD with FEV1 <50% predicted: two inhalations twice daily.

Fostair 200/6
• Adult for asthma maintenance therapy: two inhalations twice daily, with a maximum of four inhalations per day.

Fusacomb Easyhaler - Salmeterol and fluticasone propionate

Long-acting selective beta2 agonist with corticosteroid.

Fusacomb 50/250 Easyhaler
• 12 years and over for prophylaxis of asthma: one inhalation twice daily and can be reduced to once daily.
Fusacomb 50/500 Easyhaler
• 12 years and over for prophylaxis of asthma: one inhalation twice daily.
• Adult for COPD: one inhalation twice daily.

Ipramol - Ipratropium bromide with salbutamol

Antimuscarinic bronchodilator with short-acting selective beta2 agonists.

• Adult and child over 12 years for bronchospasm in chronic obstructive pulmonary disease: by inhalation of nebulised solution, 0.5/2.5 mg, 3–4 times daily.

Luforbec - Beclometasone with formoterol

Luforbec - Beclometasone with formoterol

Long-acting selective beta2 agonist with corticosteroid.

Asthma maintenance therapy for Luforbec® 100/6 by inhalation of aerosol
Adult: 1–2 inhalations twice daily; maximum 4 inhalations per day.

Asthma, maintenance and reliever therapy for Luforbec® 100/6 by inhalation of aerosol
Adult: 1 inhalation twice daily; 1 inhalation as required, for relief of symptoms; maximum 8 inhalations per day.

Chronic obstructive pulmonary disease with forced expiratory volume in 1 second < 50% of predicted for Luforbec® 100/6 by inhalation of aerosol
Adult: 2 inhalations twice daily.

Asthma maintenance therapy for Luforbec® 200/6 by inhalation of aerosol
Adult: 2 inhalations twice daily, maximum 4 inhalations per day.

Children and adolescents aged less than 18 years must not take this medicine

Relvar Ellipta - Fluticasone with vilanterol

Long-acting selective beta2 agonist with corticosteroid.

Relvar Ellipta 92 mcg/22 mcg
• Over 12 years for prophylaxis of asthma: one inhalation once daily.
• Adult for COPD: one inhalation once daily.

Relvar Ellipta 184 mcg/22 mcg
• Over 12 years for prophylaxis of asthma: one inhalation once daily.

Seffalair Spiromax - Salmeterol and fluticasone propionate

For prophylaxis of asthma with Seffalair Spiromax® 12.75/100 by inhalation of powder
Child 12–17 years: 1 inhalation twice daily.
Adult: 1 inhalation twice daily.

For prophylaxis of asthma with Seffalair Spiromax® 12.75/202 by inhalation of powder
Child 12–17 years: 1 inhalation twice daily.
Adult: 1 inhalation twice daily.

Sereflo - Salmeterol and fluticasone propionate

Long-acting selective beta2 agonist with corticosteroid.

Sereflo Ciphaler 50/250 for prophylaxis of asthma
• Over 12 years: 1 inhalation twice daily, reduced to 1 inhalation once daily, use reduced dose only if control maintained.
Sereflo 125
• Adult for moderate to severe asthma: two inhalations twice daily.
Sereflo 250
• Adult moderate to severe asthma: two inhalations twice daily.

Seretide Accuhaler - Salmeterol and fluticasone propionate

Long-acting selective beta2 agonist with corticosteroid.

Seretide 100 Accuhaler
• 4 years and over for asthma prophylaxis: one inhalation twice daily, reduce to one inhalation daily if controlled.
Seretide 250 Accuhaler
• 12 years and over for asthma prophylaxis: one inhalation twice daily.
Seretide 500 Accuhaler
• 12 years and over for asthma prophylaxis: one inhalation twice daily.
• Adult for COPD with FEV1 in one second <60% of predicted: one inhalation twice daily.
Seretide 50 Evohaler
• 4 years and over for asthma prophylaxis: two puffs twice daily, reduce to two puffs once daily if controlled.
Seretide 125 Evohaler
• 12 years and over for asthma prophylaxis: two puffs twice daily.
Seretide 250 Evohaler
• 12 years and over for asthma prophylaxis: two puffs twice daily.

Spiolto - Tiotropium with olodaterol

Antimuscarinic bronchodilator with long-acting selective beta2 agonist.

• Over 18 years for maintenance treatment of COPD: by inhalation of aerosol, two puffs once daily.

Stalpex - salmeterol and fluticasone propionate

Stalpex - salmeterol and fluticasone propionate

For severe asthma in patients 12 years of age and older only where use of a combination product (long-acting beta2 agonist and inhaled corticosteroid) is appropriate: patients not adequately controlled on a lower strength corticosteroid combination product or patients already adequately controlled on an inhaled corticosteroid in a high strength and a long-acting beta2 agonist.

  • Over 12 years: one inhalation twice daily.

For symptomatic treatment of COPD with a FEV1 <60% predicted normal (pre-bronchodilator) and a history of repeated exacerbations, who have significant symptoms despite regular bronchodilator therapy.

  • Adult: one inhalation twice daily.

Symbicort - Budesonide with formoterol (1)

Long-acting selective beta2 agonist with corticosteroid.

Symbicort 100/3 pressurised inhaler
Asthma, maintenance therapy
• Child 12–17 years: Initially 2–4 inhalations twice daily; reduced to 1 inhalation daily, dose reduced only if control is maintained.
• Adult: Initially 2–4 inhalations twice daily, increased if necessary up to 8 inhalations twice daily; reduced to 1 inhalation daily, dose reduced only if control is maintained.
Asthma, maintenance and reliever therapy
• Over 12 years: Maintenance 4 inhalations daily in 1–2 divided doses, increased if necessary up to 4 inhalations twice daily; 2 inhalations as required for relief of symptoms, increased if necessary up to 12 inhalations as required, usual max. 16 inhalations per day; up to 24 inhalations daily can be used for a limited time under medical supervision.

Symbicort 200/6 Pressurised inhaler
COPD
• Adult: 2 inhalations twice daily.

Symbicort Turbohaler - Budesonide with formetrol

Long-acting selective beta2 agonist with corticosteroid.

Symbicort 100/6 Turbohaler
• 6–17 years for asthma maintenance: 1-2 inhalations twice daily, reduced to 1 inhalation daily if controlled.
• Adults for asthma maintenance: 1-2 inhalations daily, increased to up to 4 inhalations daily if needed, or reduced to 1 daily if controlled.
• Over 12 years for asthma maintenance and reliever therapy: 2 inhalations daily across one or two doses; 1 inhalation for relief of symptoms and increase to 6 if required. A maximum of 8 inhalations per day, but 12 can be given under medical supervision.

Symbicort 200/6 Turbohaler
• 12–17 years for asthma maintenance: 1-2 inhalations twice daily, reduced to 1 inhalation daily if controlled.
• Adults for asthma maintenance: 1-2 inhalations daily, increased to up to 4 inhalations daily if needed, or reduced to one daily if controlled.
• Over 12 years for asthma maintenance and reliever therapy: 2 inhalations daily across one or two doses but can be increased to 2 inhalations twice daily if needed; 1 inhalation for relief of symptoms and increase to 6 inhalations if required. A maximum of 8 inhalations per day, but 12 can be given for a limited time under medical supervision.
• Adult for COPD: 1 inhalation twice daily.

Symbicort 400/12 Turbohaler
• 12–17 years for asthma maintenance: 1 inhalation twice daily, but can be reduced to 1 inhalation daily.
• Adult for asthma maintenance: 1 inhalation twice daily, increased to 2 inhalations twice daily if required and decreased to 1 inhalation daily if controlled.
• Adult for COPD: 1 inhalation twice daily.

Trimbow - Beclometasone with formoterol and glycopyrronium

Long-acting muscarinic receptor antagonist, long-acting selective beta2 agonist with corticosteroid.

Trimbow 87/5/9 for moderate to severe COPD or asthma maintenance therapy
Adult: 2 inhalations twice daily.

Trimbow 172/5/9 for asthma maintenance therapy
Adult: 2 inhalations twice daily.

Trimbow NEXThaler 88/5/9 for moderate to severe COPD 
Adult: 2 inhalations twice daily.

Ultibro - Glycopyrronium with indacaterol

Antimuscarinic bronchodilator with long-acting selective beta2 agonist.

• Adult for maintenance treatment of COPD: by inhalation of powder, 1 inhalation, once daily.

WockAIR - budesonide with formoterol

Long-acting selective beta2 agonist with corticosteroid.

For asthma, maintenance therapy with WockAIR® 160 mcg/4.5 mcg by inhalation of powder
Adult: Initially 1–2 inhalations twice daily, increased if necessary up to 4 inhalations twice daily; reduced to 1 inhalation daily, dose reduced only if control is maintained.

For asthma, maintenance and reliever therapy with WockAIR® 160 mcg/4.5 mcg by inhalation of powder
Adult: Maintenance 2 inhalations daily in 1–2 divided doses, increased if necessary to 2 inhalations twice daily; 1 inhalation as required, for relief of symptoms, increased if necessary up to 6 inhalations as required, max. 8 inhalations per day; up to 12 inhalations daily can be used for a limited time but medical assessment is recommended.

For chronic obstructive pulmonary disease with forced expiratory volume in 1 second < 70% of predicted (post-bronchodilator) with WockAIR® 160 mcg/4.5 mcg by inhalation of powder
Adult: 2 inhalations twice daily.

For asthma, maintenance therapy with WockAIR® 320 mcg/9 mcg by inhalation of powder
Adult: Initially 1 inhalation twice daily, increased if necessary up to 2 inhalations twice daily; reduced to 1 inhalation daily, dose reduced only if control is maintained.

For chronic obstructive pulmonary disease with forced expiratory volume in 1 second < 70% of predicted (post-bronchodilator) with WockAIR® 320mcg/9 mcg by inhalation of powder
Adult: 1 inhalation twice daily.