This website is intended for healthcare professionals
Respiratory Handbook

The professional's guide to product selection

Fluticasone (propionate)

Fluticasone (propionate)

For the prophylaxis of asthma by inhalation of powder
• Child 5–15 years: initially 50–100 mcg twice daily (maximum per dose 200 mcg twice daily), dose to be adjusted as required.
• Over 16 years: initially 100–500 mcg twice daily (maximum per dose 1 mg twice daily). Dose may be increased according to severity of asthma. Doses above 500 mcg twice daily initiated by a specialist.

For the prophylaxis of asthma by inhalation of aerosol
• Child 4–15 years: initially 50–100 mcg twice daily (maximum per dose 200 mcg twice daily), dose to be adjusted as required.
• Over 16 years: initially 100–500 mcg twice daily (maximum per dose 1 mg twice daily). Dose may be increased according to severity of asthma. Doses above 500 mcg twice daily initiated by a specialist.

For the prophylaxis of asthma by inhalation of nebulised suspension
• Child 4–15 years: 1 mg twice daily.
• Over 16 years: 0.5–2 mg twice daily.

Prophylaxis treatment of allergic and perennial rhinitis by nasal spray
• Child 4–11 years: 50 mcg once daily to be administered to each nostril preferably in the morning. Increase if necessary to 50 mcg twice daily.
• Over 12 years: 100 mcg once daily to be administered to each nostril preferably in the morning. Increase if necessary to 100 mcg twice daily. Reduce to 50 mcg once daily when controlled.
Prophylaxis treatment of nasal polyps by nasal spray
• Over 16 years: 200 mcg one to two times per
day administered into each nostril. If no improvement in four to six weeks, consider alternative treatment.

For nasal polyps using nasal drops
Over 16 years: 200 mcg 1–2 times a day, to be administered into each nostril, alternative treatment should be considered if no improvement after 4–6 weeks, (200 mcg is equivalent to approximately 6 drops).

Fluticasone propionate and salmeterol

Long-acting selective beta2 agonist with corticosteroid.

Seretide 100 Accuhaler
• 4 years and over for asthma prophylaxis: one inhalation twice daily, reduce to one inhalation daily if controlled.
Seretide 250 Accuhaler
• 12 years and over for asthma prophylaxis: one inhalation twice daily.
Seretide 500 Accuhaler
• 12 years and over for asthma prophylaxis: one inhalation twice daily.
• Adult for COPD with FEV1 in one second <60% of predicted: one inhalation twice daily.
Seretide 50 Evohaler
• 4 years and over for asthma prophylaxis: two puffs twice daily, reduce to two puffs once daily if controlled.
Seretide 125 Evohaler
• 12 years and over for asthma prophylaxis: two puffs twice daily.
Seretide 250 Evohaler
• 12 years and over for asthma prophylaxis: two puffs twice daily.

Fluticasone propionate and salmeterol - Aspire Pharma Ltd

Long-acting selective beta2 agonist with corticosteroid.

Combisal 25/125
• Over 12 years for prophylaxis of asthma: two inhalations twice daily.
Combisal 25/50
• Over 4 years for prophylaxis of asthma: two inhalations twice daily, but can be reduced to two inhalations once daily.
Combisal 25/250
• Over 12 years for prophylaxis of asthma: two inhalations twice daily.

Fluticasone propionate and salmeterol - Cipla EU Ltd

Long-acting selective beta2 agonist with corticosteroid.

Sereflo Ciphaler 50/250 for prophylaxis of asthma
• Over 12 years: 1 inhalation twice daily, reduced to 1 inhalation once daily, use reduced dose only if control maintained.
Sereflo 125 for moderate to serve asthma
• Adult: 2 inhalations twice daily.
Sereflo 250 for moderate to severe asthma
• Adult: 2 inhalations twice daily.

Fluticasone propionate and salmeterol - Glenmark Pharmaceuticals Europe Ltd

Long-acting selective beta2 agonist with corticosteroid.

Stalpex 500/50 mcg
• For symptomatic treatment of COPD with a FEV1 <60% predicted normal (pre-bronchodilator) and a history of repeated exacerbations, who have significant symptoms despite regular bronchodilator therapy.
• Adult: one inhalation twice daily.

Stalpex is indicated for use in patients with severe asthma 12 years of age and older only, where patients not adequately controlled on a lower strength corticosteroid combination product; or patients already adequately controlled on an inhaled corticosteroid in a high strength and a long-acting beta2 agonist.
• Adults and adolescents 12 years and older: One inhalation, twice daily

Fluticasone propionate and salmeterol - Orion Pharma (UK) Ltd

Long-acting selective beta2 agonist with corticosteroid.

Fusacomb 50/250 Easyhaler
• 12 years and over for prophylaxis of asthma: one inhalation twice daily and can be reduced to once daily.

Fusacomb 50/500 Easyhaler
• 12 years and over for prophylaxis of asthma: one inhalation twice daily.
• Adult for COPD: one inhalation twice daily.

Fluticasone propionate and salmeterol - Sandoz

Long-acting selective beta2 agonist with corticosteroid.

AirFluSal 125
• Adult for prophylaxis of moderate to severe asthma: two inhalations twice daily.

AirFluSal 250
• Over 18 years for prophylaxis of moderate to severe asthma: two inhalations twice daily.

AirFluSal Forspiro
• Adult for severe asthma and COPD: one inhalation twice a day.

Fluticasone propionate and salmeterol - Thornton & Ross Ltd

Long-acting selective beta2 agonist with corticosteroid.

Fixkoh Airmaster 50/250
• 12 years and over for prophylaxis of asthma: one inhalation twice daily.
Fixkoh Airmaster 50/100
• 12 years and over for prophylaxis of asthma: one inhalation twice daily but can be reduced to once daily.
Fixkoh Airmaster 50/500
• 12 years and over for prophylaxis of asthma: one inhalation twice daily.
• Adult for COPD: 1 inhalation twice daily.

Fluticasone with vilanterol

Long-acting selective beta2 agonist with corticosteroid.

Relvar Ellipta 92 mcg/22 mcg
• Over 12 years for prophylaxis of asthma: one inhalation once daily.
• Adult for COPD: one inhalation once daily.

Relvar Ellipta 184 mcg/22 mcg
• Over 12 years for prophylaxis of asthma: one inhalation once daily.

Nasofan - Fluticasone (propionate)

Prophylaxis treatment of allergic and perennial rhinitis by nasal spray
• Child 4–11 years: 50 mcg once daily to be administered to each nostril preferably in the morning. Increase if necessary to 50 mcg twice daily.
• Over 12 years: 100 mcg once daily to be administered to each nostril preferably in the morning. Increase if necessary to 100 mcg twice daily. Reduce to 50 mcg once daily when controlled.
Prophylaxis treatment of nasal polyps by nasal spray
• Over 16 years: 200 mcg one to two times per
day administered into each nostril. If no improvement in four to six weeks, consider alternative treatment.