Kalydeco - Ivacaftor

A cystic fibrosis transmembrane conductance regulator (CFTR) protein potentiator that increases chloride transport in the abnormal CFTR protein.

By mouth using granules
Child 4–5 months (body-weight 5 kg and above): 25 mg every 12 hours.
Child 6 months–17 years (body-weight 5–6 kg): 25 mg every 12 hours.
Child 6 months–17 years (body-weight 7–13 kg): 50 mg every 12 hours.
Child 6 months–17 years (body-weight 14–24 kg): 75 mg every 12 hours.

By mouth using tablets
Child 6–17 years (body-weight 25 kg and above): 150 mg every 12 hours.
Adult: 150 mg every 12 hours – specialist use only.