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Respiratory Handbook

The professional's guide to product selection

Products

Kaftrio - Tezacaftor with Ivacaftor and Elexacaftor

Mucolytic to facilitate expectoration by reducing sputum viscosity in the case of cystic fibrosis.

Kaftrio 37.5 mg/25 mg/500 mg
Child 6–11 years (body-weight up to 30 kg): 2 tablets, to be taken in the morning and, Ivacaftor 75 mg to be taken in the evening (about 12 hours apart).

Kaftrio 75 mg/50 mg/100 mg
Child over 6 years with body weight greater than 30 kgs and adult: 2 tablets to be taken in the morning in combination with Ivacaftor 150 mg in the evening.

Kalydeco - Ivacaftor

A cystic fibrosis transmembrane conductance regulator (CFTR) protein potentiator that increases chloride transport in the abnormal CFTR protein.

By mouth using granules
Child 4–5 months (body-weight 5 kg and above): 25 mg every 12 hours.
Child 6 months–17 years (body-weight 5–6 kg): 25 mg every 12 hours.
Child 6 months–17 years (body-weight 7–13 kg): 50 mg every 12 hours.
Child 6 months–17 years (body-weight 14–24 kg): 75 mg every 12 hours.

By mouth using tablets
Child 6–17 years (body-weight 25 kg and above): 150 mg every 12 hours.
Adult: 150 mg every 12 hours – specialist use only.

Kelhale - Beclometasone (beclomethasone) dipropionate

For prophylaxis of asthma by inhalation of aerosol. Kelhale has extra-fine particles and is more potent than traditional beclomethasone diproprionate inhalers.
• Adult: 50–200 mcg twice daily, increased if necessary to 400 mcg twice daily